The Rio Institute NovoRisk · WP223–24 November 2026 · Paris
Organised by
The Rio Institute École Normale Supérieure – PSL Muséum national d'Histoire naturelle
International Conference · NovoRisk Project

AI and Synthetic Biology: Environmental Risk and Governance

An interdisciplinary conference bringing together researchers in artificial intelligence, synthetic biology, environmental science, risk assessment and governance — to examine how environmental oversight can remain scientifically robust, transparent and fit for purpose as biological design becomes AI-enabled.

Dates 23–24 November 2026 Two full days
Venue École Normale Supérieure Paris, France
Format Keynotes, panels & working groups By invitation and application
Language English All sessions
Courtyard and main building of the École Normale Supérieure, Paris
The conference venue — École Normale Supérieure, Paris. Photo from the École Normale Supérieure website.

At a glance

Dates
23–24 November 2026
Venue
École Normale Supérieure (ENS–PSL), ParisRoom TBC
Organised by
The Rio Institute · École Normale Supérieure (ENS–PSL) · Muséum national d'Histoire naturelle (MNHN)
Part of
The NovoRisk project — Work Package 2
Funded by
German Federal Ministry for the Environment, Climate Action, Nature Conservation and Nuclear Safety (BMUKN), commissioned through the German Federal Agency for Nature Conservation (BfN)
Registration & enquiries

Programme.

Two days, structured for exchange.

Keynote presentations, thematic lectures, moderated panels and small-group breakout sessions — designed to surface convergence and disagreement alike, with a shared emphasis on evidence, transparency and a proportionate treatment of uncertainty.

Day 1

Monday 23 November

Morning: how AI is changing scientific and biological practice. Afternoon: how oversight institutions are responding.

09:00 – 09:30

Registration & opening remarks

Welcome from the Rio Institute, ENS-PSL and MNHN, and an introduction to the conference objectives.

Organisers · Rio Institute, ENS-PSL and MNHN
09:30 – 10:00

Keynote — Governing the convergence of artificial and environmental systems

Framing the challenge.

SV
Prof. Dr. Silja Voeneky
University of Freiburg

Prof. Dr. Silja Voeneky is Professor of Public International Law, Comparative Law and Ethics of Law at the University of Freiburg and an associated member of the Institut für Staatswissenschaft and Philosophy of Law, University of Freiburg. She was a Visiting Fellow at Harvard Law School in 2015–2016. She currently serves as a member of the German Federal Foreign Office’s Public International Law Advisory Board and of the Ethics Council of the Max Planck Society, and is appointed as an arbitrator of the Permanent Court of Arbitration (PCA).

10:00 – 10:30

Intelligence, an animal property

The thinker’s view: what counts as intelligence, and what AI does — and does not — change about scientific understanding.

Dr. Daniel Andler
Dr. Daniel Andler
Sorbonne Université · CNRS UMR8011 & DEC, ENS-PSL

Dr. Daniel Andler is a French mathematician and philosopher, Professor Emeritus at Sorbonne University and a member of the Académie des Sciences Morales et Politiques. His book “Intelligence artificielle, intelligence humaine : la double énigme” (2023) explores the philosophical and cognitive foundations of artificial intelligence, examining the nature of human and machine intelligence.

10:30 – 10:45

Coffee break

10:45 – 11:15

De novo development of antimicrobial peptides accelerated by integrating deep learning and synthetic biology

The practitioner’s view: what working with AI looks like day to day in a biology lab — where it accelerates discovery, and where it can mislead.

Dr. Amir Pandi
Dr. Amir Pandi
Inserm U1338 & CQSB, Sorbonne Université

Dr. Amir Pandi is an ATIP-Avenir group leader and head of the research group SynBAI — “Synthetic Biology and Artificial Intelligence” — at Sorbonne University. His work focuses on the development of de novo antimicrobial peptides by combining synthetic biology with machine learning.

11:15 – 12:00

Open discussion — Practitioners meet thinkers

The keynote and morning lecture speakers in conversation with the room: how is AI changing the study of science and biology, and what should we be critical of?

Amaury Lambert · ENS-PSLJoann Sy · Rio Institute
12:00 – 13:00

Lunch

13:00 – 13:30

From AI models to auditable biological design: a computational case study of agronomic trait optimisation in soybean

Dr. Gurvinder Singh Dahiya
Dr. Gurvinder Singh Dahiya
Co-founder & CTO, Syngens AS

Dr. Gurvinder Singh Dahiya is co-founder and CTO of Syngens AS, where he leads the development of its AI platform for DNA and protein design. He applies machine learning and generative AI to computational biology, with an emphasis on traceable evidence and explicit uncertainty. He has led national and international projects and deployed real-time AI services used by several million people.

13:30 – 14:00

Predictability and its limits

Model-based design of complex biological networks: what can and cannot be predicted.

Speaker to be announced
14:00 – 14:30

Uncertainty and robustness of AI predictions

What uncertainty quantification and robustness guarantees can actually certify.

Speaker to be announced
14:30 – 14:45

Q & A — early afternoon lectures

Jean-Baptiste Boule · MNHNJoann Sy · Rio Institute
14:45 – 15:00

Coffee break

15:00 – 15:45

Panel — AI & environmental risks

What changes and what does not: risk hypotheses under AI-assisted design.

Dr. Ben A. Woodcock
Dr. Ben A. Woodcock
UK Centre for Ecology & Hydrology, Wallingford, UK

Dr. Ben A. Woodcock is head of the Community & Restoration Ecology Group at UKCEH. His work considers the interface between biodiversity and productive agriculture, with a focus on the impacts of synthetic pesticides on beneficial insects. He currently runs England’s post-regulatory monitoring of pesticide exposure risks for honeybees in collaboration with the Department for Environment, Food and Rural Affairs (Defra).

TBA
Panellist to be announced
TBA
Panellist to be announced
15:45 – 16:15

Environmental releases

Post-market monitoring and general surveillance of AI-designed organisms.

Speaker to be announced
16:15 – 16:45

Q & A — environmental releases

Joann Sy · Rio Institute
16:45 – 17:00

Close of day one

Briefing on the breakout working groups and the rapporteur templates.

Jean-Baptiste Boule · MNHNJoann Sy · Rio Institute
Day 2

Tuesday 24 November

From capability to assessment — predictability and uncertainty, environmental risk assessment under complexity, AI as an oversight tool, and the breakout working groups.

09:00 – 09:30

Overview of day one, introduction to day two

Recap of emerging themes; introduction to the working method.

Sarah Agapito · Rio InstituteAmaury Lambert · ENS-PSL
09:30 – 10:00

Regulatory practice under acceleration

How an assessing authority actually handles novel dossiers, and what shorter development cycles do to that workload.

Speaker to be announced
10:00 – 10:30

Efficiency fallacy of reporting environmental sustainability of AI data centres in EU policy

Dr. Daria Onitiu
Dr. Daria Onitiu
Hasso-Plattner-Institute, University of Potsdam · Oxford Internet Institute, University of Oxford Online

Dr. Daria Onitiu is a postdoctoral researcher at the Hasso-Plattner-Institute, University of Potsdam, and a Research Associate at the Oxford Internet Institute, University of Oxford. Her research interests include the governance of AI software as a medical device, the ethics of AI in health, and the real-world challenges of the responsible use, safety and environmental sustainability of large generative AI models.

10:30 – 10:50

Q & A

Sarah Agapito · Rio InstituteAmaury Lambert · ENS-PSL
10:50 – 11:00

Coffee break

11:00 – 11:25

Probabilistic latent representation learning for Earth monitoring

Prof. Dr. Mohammed Nabil El Korso
Prof. Dr. Mohammed Nabil El Korso
Paris-Saclay University · L2S Laboratory

Prof. Dr. Mohammed Nabil El Korso is a Professor of Statistical Machine Learning and Signal Processing at Paris-Saclay University. His research focuses on statistical inference, robust signal processing and machine learning, with particular interest in learning from incomplete, noisy and mismatched data. His work spans several application areas, including climate data analysis and Earth observation. Professor El Korso has authored numerous scientific publications and is co-editor of the Springer book “Elliptically Symmetric Distributions in Signal Processing and Machine Learning” (2024). He is also actively involved in the scientific community through his editorial activities, including serving as Senior Area Editor for IEEE Signal Processing Letters and as Associate Editor for IEEE Transactions on Signal Processing.

11:25 – 11:50

Trustworthy AI for environmental oversight: uncertainty quantification and process understanding

Dr. Miguel-Ángel Fernández-Torres
Dr. Miguel-Ángel Fernández-Torres
Department of Signal Theory and Communications, Universidad Carlos III de Madrid

Dr. Miguel-Ángel Fernández-Torres is an Assistant Professor in UC3M’s Department of Signal Theory and Communications, an ELLIS Unit Madrid member, and co-leader of the ITU/UN Working Group on Data for the Global Initiative on Resilience to Natural Hazards through AI Solutions. Holding a 2019 PhD in Multimedia and Communications from UC3M alongside past research experience at Universitat de València, Purdue University, TU Munich (AI4EO) and Fraunhofer HHI, his work merges machine learning, computer vision and Earth system sciences, using deep generative models and explainable AI to monitor extreme events such as droughts, wildfires and heatwaves.

11:50 – 12:15

Q & A

Sarah Agapito · Rio InstituteAmaury Lambert · ENS-PSL
12:15 – 13:15

Lunch

13:15 – 14:20

Panel — AI & regulatory frameworks

Governance options, methodological preparedness and regulatory practice.

Dr. Michael Eckerstorfer
Dr. Michael Eckerstorfer
Environment Agency Austria (Umweltbundesamt), Vienna

Dr. Michael Eckerstorfer holds a PhD in Molecular Genetics from the University of Vienna and serves as Senior Scientific Officer in the Unit “Landuse and Biosafety” at Environment Agency Austria in Vienna. His work focuses on the environmental risk assessment and monitoring of genetically modified organisms (GMOs), including GM plants and GM microorganisms developed by new genomic techniques.

TBA
Panellist to be announced
TBA
Panellist to be announced
14:20 – 14:35

Introducing the group discussions

Reading AI-generated biological data as a regulator would.

Speaker to be announced
14:35 – 15:35

Breakout discussions

Three parallel groups on three pre-selected case studies.

15:35 – 15:55

Coffee break

16:00 – 16:40

Group presentations

Rapporteur report-back, 13 minutes per group.

16:40 – 17:00

Final remarks & conference closure

Closing reflections and next steps.

Organisers · Rio Institute, ENS-PSL and MNHN

Programme subject to change. Remaining speakers will be added to this page as they confirm.

Background & rationale.

Why this conference, and why now.

Artificial intelligence is rapidly transforming the development of genetically modified organisms, synthetic biology applications and advanced biotechnology systems — and environmental governance is being asked to keep pace.

AI-assisted approaches are increasingly used to identify target genes, design proteins, optimise metabolic pathways, model biological interactions and support multi-trait engineering strategies across agricultural, industrial and environmental applications. These developments are reshaping the innovation dynamics of biotechnology itself: accelerating design cycles, expanding the scale of combinatorial experimentation, and enabling increasingly complex forms of biological engineering.

The premise of this conference is not that current environmental risk assessment (ERA) frameworks are obsolete. Rather, the convergence of AI and biotechnology may place growing pressure on some of the operational assumptions that underpin existing governance systems — assumptions about comparators, predictability, traceability, transparency, the scalability of assessment, and the pace at which novel products emerge.

Importantly, AI may simultaneously strengthen and challenge environmental governance. While AI-assisted biological design introduces additional layers of complexity and uncertainty, AI tools may also support oversight through improved modelling, toxicity prediction, non-target organism analysis, environmental monitoring, uncertainty characterisation and large-scale data integration.

The conference therefore moves beyond narratives focused solely on regulatory insufficiency or technological optimism, and instead creates a structured interdisciplinary space to examine how environmental governance can remain scientifically robust, precautionary, transparent and operationally effective.

Objectives.

What the conference sets out to do.

The conference serves as an interdisciplinary scientific exchange platform, bringing together experts from artificial intelligence, synthetic biology, environmental science, risk assessment, governance, regulation and science-policy studies.

  1. Examine how AI is transforming the scale, speed and logic of biological engineering.
  2. Identify which assumptions and methodologies within existing environmental governance frameworks may face increasing pressure under AI-enabled biotechnology trajectories.
  3. Evaluate which aspects of current ERA frameworks remain scientifically robust and applicable.
  4. Explore scientifically grounded options for strengthening governance readiness, transparency, oversight capacity and methodological preparedness.
  5. Examine how AI itself may contribute to environmental risk assessment and oversight processes.
  6. Develop forward-looking governance considerations and research priorities relevant to regulators, researchers and international policy processes.

Conference themes.

Four interconnected dimensions.

The analytical framework is structured around four dimensions, examined through interdisciplinary dialogue connecting the life sciences, AI research, environmental science, governance scholarship and regulatory practice.

Theme A

Transformation of biotechnology innovation dynamics

How is AI changing the scale, speed, design logic and innovation pathways of biotechnology and synthetic biology?

Theme B

Environmental risk assessment under increasing complexity

Which operational assumptions within current ERA frameworks may become increasingly challenged by AI-assisted biological design — including comparators, transparency, combinatorial complexity, system interactions and accelerated development cycles?

Theme C

Governance readiness and oversight capacity

How can governance systems maintain robust oversight, transparency, traceability, accountability and precaution in contexts involving increasing biological and computational complexity?

Theme D

AI as a tool for environmental oversight

How might AI strengthen environmental risk assessment and monitoring — through predictive modelling, ecological analysis, toxicity prediction, environmental monitoring, uncertainty characterisation and data integration?

Practical information.

Venue & participation.

The conference is hosted by the École Normale Supérieure in Paris — one of France's most selective institutions for research and higher education — which is also a co-organiser, alongside the Rio Institute and the Muséum national d'Histoire naturelle (MNHN), one of France's foremost research institutions in natural history and biodiversity science.

Places are limited. Registration and further practical details will be confirmed closer to the event — write to the organiser to be added to the list.

Venue
École Normale Supérieure (ENS–PSL)
Address
Paris, FranceBuilding & room TBC
Dates
Monday 23 – Tuesday 24 November 2026
Language
English (all sessions)
Participation
In person, by invitation and applicationOnline option TBC
Registration

Registration & enquiries.

Get more information, or ask us anything.

Registration is handled directly by the conference organiser. Write to Joann Sy to reserve a place, to request the concept note, or to ask about the programme, the venue or participation.

Conference organiser
Joann Sy
Policy Director, The Rio Institute
Email

joann.sy@rioinstitute.eu

Funded by
German Federal Ministry for the Environment, Climate Action, Nature Conservation and Nuclear Safety (BMUKN) German Federal Agency for Nature Conservation — Bundesamt für Naturschutz (BfN)

The NovoRisk project is funded by the German Federal Ministry for the Environment, Climate Action, Nature Conservation and Nuclear Safety (BMUKN), commissioned through the German Federal Agency for Nature Conservation (BfN).